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Immune Deficiency Foundation

Immune Deficiency Foundation

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This podcast is a service of the Immune Deficiency Foundation — a nonprofit organization dedicated to improving the diagnosis, treatment, and quality of life of people diagnosed with primary immunodeficiency, or PI. "Bold Conversations" is a program that explores the harsh realities of health access in the United States. Hosted by Dr. Nicole Rochester. "Undiagnosed" is a narrative docuseries on that tells the true stories of PI patients and their long journeys to proper diagnosis and treatme ...
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Hello and welcome to Untangling PANDAS & PANS, a podcast about two relatively unknown medical disorders characterized by the sudden and dramatic onset of obsessions and compulsions, vocal or motor tics, or restricted eating behavior -- and a whole host of other symptoms -- following strep or other bacterial or viral infection. Sometimes overnight. I have the privilege of interviewing some of the top researchers and clinicians in the rapidly growing field of Infection-Associated, Immune-Media ...
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This podcast series introduces i-MPACT, a multifaceted program which aims to improve the care of patients treated with immunotherapy, while providing a better understanding of the pathophysiology associated with immune-related adverse events. Each episode features an interview with a leading expert discussing proactive, longitudinal care, as well as the potential for irAEs following treatment with immunotherapy and current toxicity management strategies.
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The Immune System Podcast

Sankalpa Chakma

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The immune system is extremely vital for the proper functioning of our body, and important as it is, it also remains somewhat of an enigma to many of us, scientists included. With this podcast, I try to throw some light on this topic, though I must say I’m no expert authority on it, in fact quite far from it, I’m just as clueless as anyone else.
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Become a Paid Subscriber: https://podcasters.spotify.com/pod/show/evelyn-eve4/subscribe Become a Paid Subscriber: https://anchor.fmevelyn-eve4/subscribe Become a Paid Subscriber: https://anchor.fm/evelyn-eve4/subscribe Become a Paid Subscriber:
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If you’ve ever felt guilty for saying no, this one’s for you. Let’s talk about why living with chronic illness is a full-time job—and how setting boundaries can save your energy (and your sanity). Plus, I’ve got a brand-new resource to help: The Boundaries Reset Workbook. Memorable Quotes: “Chronic illness is a full-time job—with no PTO, no weekend…
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In this powerful episode of Untangling PANDAS and PANS, host Susan Manfull, PhD sits down with Jen, a resilient young woman whose health took a devastating and mysterious turn in her early twenties. From being taken out of work on a stretcher—twice—to struggling for answers amidst an array of debilitating physical and psychiatric symptoms, Jen shar…
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Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and …
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In this episode, I’m joined by Nicole Roth—a Health Restoration & Joy Coach and longtime autoimmune warrior—who shares how she reclaimed her health and joy after years of living with Hashimoto’s. We talk about the power of mindset, the role of boundaries in healing, and how faith and nervous system regulation helped her shift from seeing herself as…
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Let’s get real: not all entrepreneurs start their day with a latte and a color-coded calendar. Some of us start it from bed—with heating pads, pill bottles, and a to-do list that flexes with our energy. In this episode, I’m sharing how I run a business while managing chronic illness, why “business as usual” doesn’t work for spoonies, and how to cre…
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I know this wasn’t the most uplifting episode—but I also know how lonely it feels to sit with scary lab results, unanswered questions, and a body that’s just not cooperating. So if you’re there right now too, please know: I see you. You’re not broken. You’re not failing. And you don’t have to face the unknown alone. Whether your kidneys are flaring…
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From the 2024 Society for Leukocyte Biology meeting, Immune talks with Holger Heine about the discovery of immune recognition of bacterial lipopolysaccharide and innate immunity to organisms within the kingdom Archaea. Hosts: Cindy Leifer and Brianne Barker Guest: Holger Heine Become a patron of Immune! Links for this episode MicrobeTV Discord Serv…
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Transcript: https://primaryimmune.org/sites/default/files/Transcript%20Shaker.pdfDr. Marcus Shaker is a professor of pediatrics in medicine at Dartmouth's Geisel School of Medicine. On this episode of the Immune Deficiency Foundation podcast, he joined staff members Angie Kotarski, community resource navigator, and Stephanie Steele, director of pay…
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Today’s episode is for the ones who miss their old selves—the energetic version who stayed out late, made spontaneous plans, and didn’t have to count spoons just to take a shower. Chronic illness brings a grief that no one prepares you for. It’s not linear, it’s not loud—but it’s real. We talk about what this grief looks like, why it comes in waves…
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Ever felt completely alone, even in a room full of people? This episode is all about that invisible ache—loneliness that isn’t about being physically alone, but about not feeling understood. When you’re living with a chronic illness, especially one others can’t see, that kind of isolation can run deep. I’m sharing a personal story that hit me hard …
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Immune talks with David Peterson and Kim Klonowski from the University of Georgia about their careers, their People, parasites, and plagues podcast, placental malaria immunity, and and how interferons in the thymus affect T cell repertoire selection. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Guests: David Peterson an…
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Transcript: https://primaryimmune.org/sites/default/files/Advocacy%20Day%20Training%20Transcript.pdfThis week, 150 advocates will represent the Immune Deficiency Foundation and the greater PI community on Capitol Hill in Washington, D.C. But what does that mean, exactly? Why is it important? And what are these volunteers responsible for? This episo…
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In this illuminating conversation, Dr. Sarah O'Dor—Harvard instructor and Director of Research at Massachusetts General Hospital's PANDAS Clinic—reveals how strep infections and other triggers can cause sudden, dramatic psychiatric symptoms in children and young adults. Dr. O'Dor paints a vivid picture of PANDAS (Pediatric Autoimmune Neuropsychiatr…
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Transcript: https://primaryimmune.org/sites/default/files/TRANSCRIPT%20Legislative%20webinar.pdfThis panel discussion features Immune Deficiency Foundation CEO Jorey Berry, as well as Chief Public Policy Officer Lynn Albizo, Community Resource Navigator Angie Kotarski, and Jodi Taub, owner of Jodi Taub Therapy, discuss the impact of recent federal …
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In this episode, we’re talking about the power of gratitude—not as toxic positivity, but as a tool to find hope and joy even on the hardest days. You’ll learn how gratitude rewires your brain, helps shift your focus, and creates space for both the pain and the good. 💛 Memorable Quotes: “Hope and joy feel so out of reach sometimes. But gratitude doe…
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In this first episode, I share my journey to getting diagnosed with Ankylosing Spondylitis and Fibromyalgia after years of being dismissed. I also talk about why I started The Invisible Illness Club Podcast and what you can expect—real, honest conversations about chronic illness, faith, and finding joy in the hard moments. You’re not alone here! Me…
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https://primaryimmune.org/sites/default/files/Bold%20Conversations%203.2%20Transcript.pdfIn this session from the 2024 PI Conference in Chicago, Dr. Nicole gave a very vulnerable talk about her experiences navigating the healthcare system, both as a physician and as a caregiver for her father. To learn more, volunteer, or donate, visit primaryimmun…
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From the 2024 Society for Leukocyte Biology meeting, Immune talks with Amy Hise about her career in science, her current research using mouse models for investigating fungal immunity and navigating the challenges of being a mom in science. Hosts: Cindy Leifer and Brianne Barker Guest: Amy Hise MicrobeTV Discord Server Mouse model for testing drugs …
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Transcript: https://primaryimmune.org/sites/default/files/01PROOF%20transcription%20gene%20editing%20webinar.pdfView a PDF of this presentation: https://primaryimmune.org/sites/default/files/FOR%20WEB%20-%20Gene%20editing.pdfSusan Prockop, MD​ of Boston Children's Hospital and Harvard Medical School provides an overview and recent updates to gene t…
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This podcast episode features an interview with Dr. Brent Harris, the Director of Neuropathology at Georgetown University where he wears many hats, including overseeing the Georgetown Brain Bank. In 2020, he accepted the brain of Alex Manfull who had died from complications due to PANDAS and, eventually, with the help of The Alex Manfull Fund, esta…
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Immune 90: Immunology of Injury March 25, 2025 From the 2024 Society for Leukocyte Biology meeting at Michigan State University, home of the Spartans, Immune’s Cindy and Brianne talk with Liz Kovacs and Jim Lederer about their careers, dirty mice, old mice, and immunity during trauma. Hosts: Cindy Leifer and Brianne Barker Guests: James Lederer and…
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Transcript: https://primaryimmune.org/sites/default/files/FOR%20WEB%20Undiagnosed%20Ilana%20Transcript.pdfTikTok personality and author of "Medical Gaslighting" Ilana Jacqueline has captivates her curious followers with tips on navigating a hostile medical system. Unfortunately, her lessons are often things she's learned the hard way. Medical gasli…
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In this episode of On AIRR, Dr. Bjoern Peters, Professor at the La Jolla Institute for Immunology (LJI), explores how high-quality data serves as the foundation for advancing AI-based immunological predictions and diagnostics. Originally from Germany, Dr. Peters began his academic journey in theoretical physics at Hamburg, focusing on quantum optic…
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Immune Booster #10 HIV in the brain with Amanda Brown March 18, 2025 From the The Society for Leukocyte Biology 2024 conference at Michigan State University, Cindy and Brianne sit down with Amanda Brown from Johns Hopkins School of Medicine to talk about her career and the research of her laboratory on mechanisms of neuroinflammation in disease, es…
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Transcript: https://primaryimmune.org/sites/default/files/Cx20%201.1%20transcript.pdf.Immune Deficiency Foundation volunteers Riley and Nick discuss the complications and strategies that helped them transition from pediatric to adult care for their chronic illnesses.The information, terminology, and opinions presented in this forum do not necessari…
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Immune discusses how non-neutralizing antibodies can still be protective…intracellularly, and a technically innovative paper that uses Lipstic to label antigen-presenting cells responsible for gut tolerance to food antigens. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become…
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Dr Herb Lachman is a physician, behavioral geneticist, and professor at the Albert Einstein College of Medicine in New York City. In his 44 years on the faculty, he has studied the molecular basis of schizophrenia, autism, and the broad category of neurodevelopmental disorders. More recently, a serendipitous inquiry about a major DNA Damage Respons…
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Transcript: https://primaryimmune.org/sites/default/files/Bold%20Conversations%203.1%20Transcript.pdfJalisa Clark is a Research Fellow at the Center on Health Insurance Reforms (CHIR) at Georgetown University’s McCourt School of Public Policy. Today, she joins Dr. Nicole for a deep dive into inequitable health insurance practices in the U.S.The inf…
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Are you feeling overwhelmed, unseen, or just plain exhausted from navigating life with a chronic illness? You’re not alone, and this podcast is here to remind you of that. Welcome to The Invisible Illness Club Podcast, a space where your struggles are acknowledged, your wins (big or small) are celebrated, and real-life solutions meet hope and encou…
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Dr. Thierry Mora and Dr. Aleksandra Walczak co-lead the Statistical biophysics group within Laboratoire de physique de l'ENS (LPENS) at the Ecole normale supérieure (Paris, France). Physicists by training, Dr. Mora and Dr. Walczak entered the field of the analysis of the immune system in a time when the first AIRR-seq datasets were becoming availab…
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Immune describes the use of bespoke antibodies to characterize immune cell populations in cave nectar bats, and co-option of retrotransposons to activate hematopoietic stem cells and erythropoiesis. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links…
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Juliette C. Madan, MD, MS wears many hats. Dr. Madan is an Associate Professor of Pediatrics, Psychiatry, Epidemiology, and Quantitative Biomedical Data Science at Geisel School of Medicine at Dartmouth. She is the Clinical Director of the Children’s Environmental Health and Disease Prevention Research Center within Geisel and Dartmouth Hitchcock M…
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Transcript: https://primaryimmune.org/sites/default/files/Mental%20health%20tips.pdfBecky Lenning is the owner and clinical director of Yellow Lotus Clinical Services for Healing and Wellness, where she brings over fourteen years of clinical experience as a licensed professional counselor to her practice.To learn more, volunteer, or donate, visit p…
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Immune discusses basophils as regulators of of lung inflammation over space and time, and neoself-antigens as the primary target for autoreactive T cells in human lupus. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV D…
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Dr. Warris Bokhari, CEO and co-founder of the insurance appeals platform Claimable, discusses how the product is helping patients with PANDAS and PANS diagnoses fight denied healthcare claims. He explains the process of using Claimable to submit comprehensive appeals that cite medical research and leverage State laws, resulting in an 85% success ra…
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CONTENT WARNING: This episode contains discussions of suicide planning. If you need help, call the National Suicide Hotline at 988.Transcript: https://primaryimmune.org/sites/default/files/Undiagnosed%20Matt%20Lesser%20Transcript.pdf.The story of Matt Lesser is one that's marked, of course, by persistence, but also by vulnerability, self reflection…
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